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Shimada, Kazumasa; Kai, Michiaki*
Journal of Radiological Protection, 35(4), p.763 - 775, 2015/12
Times Cited Count：16 Percentile：79.46(Environmental Sciences)This paper has proposed that disability-adjusted life year (DALY) can be used as a measure of radiation health risk. DALY is calculated as the sum of years of life lost (YLL) and years lived with disability (YLD). This multidimensional concept can be expressed as a risk index without a probability measure to avoid the misuse of the current radiation detriment at low doses. In this study, we calculated YLL and YLD using Japanese population data by gender. DALY for all cancers in Japan per 1 Gy per person was 0.84 year in men and 1.34 year in women. When we calculated the ICRP detriment from the same data, DALYs for the cancer sites were similar to the radiation detriment in the cancer sites, excluding leukemia, breast and thyroid cancer. A big advantage over the ICRP detriment is that DALY can calculate the risk components for non-fatal diseases without the data of lethality. This study showed that DALY is a practical tool that can compare many types of diseases encountered in public health.
March 31, 2005Department of Health Physics; Safety Division, Naka; Safety Division, Takasaki; Radiation Control Division, Oarai; Safety Division, Kansai; Operation Safety Administration Division, Mutsu
JAERI-Review 2005-028, 232 Pages, 2005/08
JAERI-Review-2005-028.pdf:13.23MB
no abstracts in English
Pinak, M.
JAERI 1346, 25 Pages, 2004/12
Molecular dynamics (MD) studies on several radiation damages to DNA - thymine dimer, thymine glycol8-oxoguanine and their recognition by repair enzymes are introduced in order to describe on the stepwise description of molecular process observed at radiation lesion sites. In all cases the significant structural changes in the DNA double helical structure were observed: (a) the breaking of hydrogen bonds network between complementary bases and resulting opening of the double helix (8-oxoguanine); (b) the sharp bending of the DNA helix centered at the lesion site (thymine dimer, thymine glycol); and (c) the flipping-out base on the strand complementary to the lesion (8-oxoguanine). The specific values of electrostatic interaction energy were found at the lesion sites (thymine dimmer: -10kcal/mol, thymine glycol: -26kcal/mol, 8-oxoguanine: -48kcal/mol).
March 31, 2004Department of Health Physics; Safety Division, Naka; Safety Division, Takasaki; Radiation Control Division, Oarai; Safety Division, Kansai; Operation Safety Administration Division, Mutsu
JAERI-Review 2004-024, 209 Pages, 2004/11
JAERI-Review-2004-024.pdf:26.17MB
no abstracts in English
Pinak, M.
JAERI-Conf 2003-011, 113 Pages, 2003/09
JAERI-Conf-2003-011.pdf:10.08MB
The workshop "International Workshop on Radiation Risk and its Origin at Molecular and Cellular Level" was held at The Tokai Research Establishment, Japan Atomic Energy Research Institute, on the 6th and 7th of February 2003. The Laboratory of Radiation Risk Analysis of JAERI organized it. This international workshop attracted scientists from several different scientific areas, including radiation physics, radiation biology, molecular biology, crystallography of biomolecules, modeling and bio-informatics. Several foreign and domestic keynote speakers addresses the very fundamental areas of radiation risk and tried to establish a link between the fundamental studies at the molecular and cellular level and radiation damages at the organism. The symposium consisted of 13 oral lectures, 10 poster presentations and panel discussion. The 108 participants attended the workshop. This publication comprises of proceedings of oral and poster presentations where available. For the rest of contributions the abstracts or/and selections of presentation materials are shown instead.
*; Asano, Yoshihiro; *; Sudo, Norimichi*
SSR-93-002, 0, 67 Pages, 1993/12
no abstracts in English
